Brad Pitt Angelina Jolie Relationship Updates: Actress Opens Up About Marriage With Hubby; 'We Have Our Issues'

Angelina Jolie talks about her marriage with Brad Pitt and her recent collaboration with the actor in the upcoming movie, By The Sea, their first ever appearance together since the 2005 film, Mr and Mrs Smith where they first met and fell in love.

In an interview with Vogue for the mag's November issue, the 40-year old actress insists that the film is not autobiographical as what sources earlier said particularly stating that the plot mirrors their troubled marriage.

"It's not autobiographical. Brad and I have our issues," she offers, "but if the characters' were even remotely close to our problems we couldn't have made the film," she said smilingly.

Angie further said that she derived inspiration for her film from her mother's life story as she faced struggles being a solo parent to raise Angelina and her brother Bertrand when their father, Jon Voight left them.

My mother was an Earth Mother and the nicest person in the world. But the specific grief came from the woman I was closest to, seeing her art slip away, her body fail her," she said pointing out the parallels between her mother, being an actress and the movie's character, Vanessa who used to be a dancer but is now grieving in the story and entertains suicidal fantasies.

Rumors of marriage troubles have always been tailing Brangelina with last week's tabloid gossips saying that the actress is jealous with Sienna Miller's participation in Brad's film, The Lost City of Z.

The actress is said to have been enraged when Brad, the movie producer, plans to fly to Ireland's movie set and had a chance to see the blonde actress together with other actors, Charlie Hunnam, and Robert Pattinson.

"'You're not going.' She's heard Brad bring up Sienna's name almost every day since the film went into production in August," a source said as mentioned in Radar Online.

Meanwhile, the actress-director also talks about her preventive surgery to decrease her likelihood to have cancer, a disease that has led to her mother's death at 49.

They are not easy surgeries. The ovaries are an easy surgery, but the hormone changes - interesting. Both of the women in my family, my mother and my grandmother started dying in their 40s. I'm 40. I can't wait to hit 50 and know I made it, she said as mentioned in 9News.com.au.

By The Sea is slated to be released in US theaters on November 13.