Paracetamol Can Sterilize Unborn Boys, Fertility Study

Women taking Paracetamol during pregnancy run the risk of affecting fertility of unborn boys, a new study claims.

Researchers at University of Edinburgh tested testosterone production in mice grafted human testicle tissue only to find that production reduced by 45 percent after seven days of exposure at a typical dose. Testosterone is not only crucial for male fertility, but also tied to well-being in males.

"We would advise that pregnant women should follow current guidance that the painkiller be taken at the lowest effective dose for the shortest possible time," said Dr. Rod Mitchell at the university.

The researchers found that testosterone production was not affected after 24 hours of Paracetamol exposure but found the decrease only after seven days, indicating that prolonged exposure even at low doses can affects the male fetus.

The study's authors have recommended that expectant mothers should follow existing guidelines that painkiller be taken at the lowest effective dose for the shortest possible time.

Paracetamol is commonly used to manage pain during pregnancy. Pregnant women are frequently prescribed the medication under the assumption that it is safe at lower doses even when taken for longer periods.

However, pregnant women are often advised to avoid taking any medication, particularly during the first three months of pregnancy when fetal development is in its most important phase.